All posts by Richard

Say what you mean and mean what you say

humpty_thumb

Have you considered an egg?

Consider Humpty Dumpty, the world’s most famous egg.

I poached the following passage from Lewis Carroll’s Through the Looking-Glass (1872), where Humpty discusses semantics and pragmatics with Alice.

“I don’t know what you mean by ‘glory’,” Alice said.

Humpty Dumpty smiled contemptuously. “Of course you don’t – till I tell you. I meant ‘there’s a nice knock-down argument for you!'”

“But ‘glory’ doesn’t mean ‘a nice knock-down argument’,” Alice objected.

“When I use a word,” Humpty Dumpty said, in rather a scornful tone, “it means just what I choose it to mean – neither more nor less.”

“The question is,” said Alice, “whether you can make words mean so many different things.”

“The question is,” said Humpty Dumpty, “which is to be master – that’s all.”

What an egg-otist! Whosoever exalteth himself shall be abased. It’s no wonder Humpty Dumpty had a great fall.

A long time ago I was a philosophy student at Otago University. And one exam time I was looking at some past exam papers and came across the following exam question: What is the meaning of a word?

It’s a simple question with a simple answer. The meaning of a word is determined by the conventions that govern its use. This is no mere platitude. It’s philosophical orthodoxy and has been since David Lewis – ranked by his peers as the third most important philosopher of the twentieth century – published Convention: A Philosophical Study (1969). Platitude. Orthodoxy. Truth.

The meaning of a word is determined by the conventions that govern its use.

Alice is right. ‘Glory’ doesn’t mean ‘a nice knock-down argument’. You can’t make words mean so many different things. You can’t make ‘glory’ mean ‘a nice knock-down argument’ on your own, any more than you can determine the next government by casting a single vote. What’s more, one of the conventions that governs the use of the term ‘glory’ is the convention of correcting people when they use the word to mean something else. Our linguistic conventions have a built-in inertia that safeguards our very ability to communicate.

Humpty Dumpty’s semantics was scrambled a long time before he met the same fate.

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Sense of Life Objectivists (SOLO) is the world’s foremost forum for disciples of Ayn Rand. Go there and check out the banner at the top-right of every page. Every few page loads it advises

Say what you mean, and mean what you say

It’s good advice. But, SOLO being the hive of hypocrisy that it is, well, you’d hardly expect its delusional denizens to take it, would you? No, you wouldn’t and they don’t.

Recently, I’ve been following (one side of) a conversation on SOLO. An Objectivist said this.

What did you understand I meant by “human (i.e. existential) survival”? Let me tell you, because I think you misinterpreted me. I meant what Ayn Rand meant by it, namely, living in accordance with man’s identity as having the potential to be a heroic being

This has the more general form.

What did you think I meant by ‘X’? I meant ‘Y’.

To which I respond, if you meant ‘Y’, why didn’t you find the word or words which actually mean what you meant, and use those instead? To enter into a philosophical discussion is to commit to upholding certain standards of rational debate. It is inexcusable to say ‘X’ when you mean ‘Y’. I know, I’ve done it myself. I’ve said ‘X’ when I meant ‘Y’. And I’ve apologised. There is simply no excuse for not saying what you mean, let alone any entitlement to use words any which way. Why should other participants in the debate have to take time out to establish the meaning of your every utterance? It’s an imposition.

There’s another problem. Words have meanings. Their meanings are determined by the conventions that govern their use. Their meanings are not determined by you on an ad lib basis as you see fit on any given occasion. Consider the case of someone who habitually says ‘X’ but means something else. (In other words, consider an Objectivist.) The Objectivist tells us he actually meant ‘Y’. But what does he mean by ‘Y’? Perhaps by ‘Y’ he means ‘Z’?

This can go two ways. One is an infinite regress of stipulative definitions. The other is a regress that stops when the Objectivist tells you that what *he* actually means is the same as what the *words* he uses actually mean. But if the Objectivist is demonstrably capable of using words to mean what the words mean, as he is in the latter case, he is without excuse for not using words to mean what they actually mean in the first place.

We use words to talk about reality. The constant redefinition of ordinary words that goes on in Objectivist circles has the inevitable consequence that the relations of reference that obtain between words and the world come unstuck.

Ayn Rand described herself as an advocate of reason. I know what ‘reason’ means. I don’t know what Rand meant by ‘reason’ but I know what she didn’t mean. She didn’t mean reason.

The human condition

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The human condition. We’ve all got it.

I’m almost surprised that the human condition didn’t make it into the APA’s recently released DSM-5. The DSM-5 is the is the fifth edition of the Diagnostic and Statistical Manual of Mental Disorders. The APA is the American Psychiatric Association and the vanguard in the medical profession’s quest to medicalise all aspects of everyday life. If you think I’m being cynical, just read the DSM-5. You’re in it. And so are all your friends. We’re all in it together. The human condition.

What’s that you say? You read the DSM-5 cover to cover and you’re not in it? Sounds diagnostic to me! Clearly, you’re in denial. Denial’s symptomatic of half the mental disorders in the book! So I’m afraid you’re only fooling yourself. But never fear, the APA is here! Here to help you trade denial for acceptance and cold comfort for change. Soon everything will be all right. The struggle will be finished. You’ll win victory over yourself and love the APA.

Are we feeling comfortably numb yet?

I’ve always felt trapped by the human condition. Even to the point of contemplating knocking on the wrong door. But, thank God, I’ve always thought outside the box I’m stuck in, too. And here’s today’s Q&A. What to do about the human condition? There is NO dilemma. Denial or acceptance? A pox on both their houses! There is a third way. Transcendence. Not as in some mystical cop-out. As in break out of the box and set yourself free!

I’ve always wanted to be more God-like.

Of course, I haven’t always been a Christian but, one way or another, I’ve always been a transhumanist. Christianity is a doctrine of transcendence and the recommended (and only) path. But even if you don’t agree—and I know many of you are averse to “religion”—would you please at least make sure you’re signed up to some other transhumanism? Join me. Otherwise, who let you out? Back in your box!

Sin of ignorance? Upgrade now to sin of culpable ignorance! Free voucher.

sin_upgrade_voucher

False belief? Could be a simple mistake. You don’t know any better.

But what if you act on it? Then it’s a false pretext. Could be a sin of ignorance. You should know better than that.

What if I tell that you’re wrong and tell you why you’re wrong—but you persist in the error of your ways? Then you commit a sin of culpable ignorance.

Let’s be clear. We’re not talking Lutheran trifles here. A sin of culpable ignorance is a mortal sin. (‘Mortal’ as in brain death. Yours.) Your offending isn’t at the lower end of the scale. It’s at the other end of the scale. You haven’t merely offended, you’ve blatantly violated. You have declared yourself an enemy of Reason and an enemy of God. Blasphemy! You have taken the name of Reason—the Lord thy God (or, if you prefer, your Only Absolute)—in vain and broken the Third Commandment.

Thomas Jefferson got it.

Fix reason firmly in her seat, and call to her tribunal every fact, every opinion. Question with boldness even the existence of a god; because, if there be one, he must more approve the homage of reason, than that of blindfolded fear.

It’s a shame that Jefferson didn’t read this before he put pen to paper. To *say* in your heart, “There is no God,” is foolishness. But to *argue* God’s non-existence is in its very nature an act of worship! (And thereby self-refuting!) Gobsmack!

What about Ayn Rand? She said she got it. She paid a fortune in lip service. But flattery gets you nowhere. Inference takes you places! So is Objectivism the road to nowhere or are Objectivists on a hiding to nothing? Yes, indeed.

I am not primarily an advocate of capitalism, but of egoism; and I am not primarily an advocate of egoism, but of reason. If one recognizes the supremacy of reason and applies it consistently, all the rest follows.

This—the supremacy of reason—was, is and will be the primary concern of my work, and the essence of Objectivism. Reason in epistemology leads to egoism in ethics, which leads to capitalism in politics.

Did you just feel a puff of air? That was Satan spreading his wings. But this time it ain’t no laughing matter. The greatest intellectual saboteur of all time, operating deep within Reason’s inner sanctum, is now exposed as traitor to the true Royal cause. Objectivism is the philosophy of reason all right – reason with a silent ‘T’.

Own up. Take a look at yourself.

I love this scripture.

To some who were confident of their own righteousness and looked down on everyone else, Jesus told this parable:

“Two men went up to the temple to pray, one a Pharisee and the other a tax collector. The Pharisee stood by himself and prayed: ‘God, I thank you that I am not like other people—robbers, evildoers, adulterers—or even like this tax collector. I fast twice a week and give a tenth of all I get.’

“But the tax collector stood at a distance. He would not even look up to heaven, but beat his breast and said, ‘God, have mercy on me, a sinner.’

“I tell you that this man, rather than the other, went home justified before God. For all those who exalt themselves will be humbled, and those who humble themselves will be exalted.” (NIV)

Oh, Lord. It’s hard to be humble.

Party pills now on sale at supermarkets

pepe

Party pills are now on sale at supermarkets. You know, the ones that

assist you in remaining ALERT and WIDE AWAKE!

and that

relieve mental fatigue, drowsiness and general inertia, keeping you BRIGHT and ALERT!

NO-DOZ® AWAKENERS. $7.45 for a box of 24 tablets. Way better value than Cosmic Corner’s Pepe party pills which go for a cool $25 per 4-pack.

Focus, energy and a clear head. These guys are great for sports, study, shift work, or partying and are OK with alcohol.

I got my NO-DOZ® AWAKENERS at the local New World. But you can shop smarter and get them online at Countdown for only $6.79.

SHARPEN UP WITH NO-DOZ!

exhorts Countdown.

EACH TABLET HAS THE SAME AMOUNT OF CAFFEINE AS A CUP OF COFFEE, GIVING YOU THAT EXTRA KICK NEEDED TO KEEP YOU GOING

no-doz

The active ingredient in both products is caffeine. NO-DOZ® AWAKENERS contain 100 mg caffeine per tablet. (And glucose.) Pepe contains caffeine in an unstated amount. (And black pepper extracts, vitamin B6 and a proprietry blend of amino acids.)

So what does this have to do with the Psychoactive Substances Act?

Section 9 of the Act gives the meaning of psychoactive substance.

9 Meaning of psychoactive substance
(1) In this Act, unless the context otherwise requires, psychoactive substance means a substance, mixture, preparation, article, device, or thing that is capable of inducing a psychoactive effect (by any means) in an individual who uses the psychoactive substance.

On the face of it, that includes both NO-DOZ® AWAKENERS and Pepe and their active ingredient caffeine.

Section 5 of the Act gives its application.

5 Application of Act
(1) This Act applies to the importation, manufacture, sale, supply, or possession of a psychoactive substance or approved product for the primary purpose of inducing a psychoactive effect in an individual who uses the substance or product.

On the face of it, the Act applies to both products and their active ingredient caffeine.

But Section (9)(3) of the Act tells us that the Act does not apply to any dietary supplement or to any food.

Cosmic Corner hopes that the Act does not apply.

our understanding is that it will not affect products which are classed as herbs or dietary supplements. For example, caffeine has a psychoactive effect, but it is classed as a food product/dietary supplement. This means the COSMIC range of party pills should continue to be available because their ingredients are classed as dietary supplements and herbs.

So does the Act apply? I don’t know. But I do know that Cosmic Corner has submitted an application for an interim product approval and presumably paid the $10,000 application fee. If their application is either approved or declined (rather than returned and the fee refunded) then I expect the Ministry of Health to come down on New World, Countdown and any other supermarket chain selling the unapproved product NO-DOZ with the full force of the law, i.e., a $500,000 fine per supermarket. (Troughers gotta fill the coffers.)

Silly supermarkets. You don’t go selling caffeine “for the primary purpose of inducing a psychoactive effect.” You’ve got to be way more subtle than that. Here’s how it’s done.

The Lord is my refuge

Whoever dwells in the shelter of the Most High
   will rest in the shadow of the Almighty.
I will say of the Lord, “He is my refuge and my fortress,
   my God, in whom I trust.”

Surely he will save you
   from the fowler’s snare
   and from the deadly pestilence.
He will cover you with his feathers,
   and under his wings you will find refuge;
   his faithfulness will be your shield and rampart.
You will not fear the terror of night,
   nor the arrow that flies by day,
nor the pestilence that stalks in the darkness,
   nor the plague that destroys at midday.
A thousand may fall at your side,
   ten thousand at your right hand,
   but it will not come near you.
You will only observe with your eyes
   and see the punishment of the wicked.

If you say, “The Lord is my refuge,”
   and you make the Most High your dwelling,
no harm will overtake you,
   no disaster will come near your tent.
For he will command his angels concerning you
   to guard you in all your ways;
they will lift you up in their hands,
   so that you will not strike your foot against a stone.
You will tread on the lion and the cobra;
   you will trample the great lion and the serpent.

“Because he loves me,” says the Lord, “I will rescue him;
   I will protect him, for he acknowledges my name.
He will call on me, and I will answer him;
   I will be with him in trouble,
   I will deliver him and honor him.
With long life I will satisfy him
   and show him my salvation.” (NIV)

Research chemicals

research_chemical

What are research chemicals? Wikipedia says

Research chemicals are chemical substances used by scientists for medical and scientific research purposes. One characteristic of a research chemical is that it is for laboratory research use only. A research chemical is not intended for human or veterinary use.

I first encountered the term on Erowid—the original go-to website for recreational drug users and “a trusted resource for drug information—both positive and negative”—and here’s what Erowid has to say about research chemicals.

Chemicals marked on Erowid by our Research Chemical Symbol should be considered experimental chemicals. Although some people are willing to ingest these chemicals for their effects, it is not reasonable to assume that these chemicals are in any way ‘safe’ to use recreationally. Although all psychoactive use involves risk, this class of chemicals has undergone virtually no human or animal toxicity studies and there is little to no data on possible long term problems, addiction potential, allergic reactions, or acute overdoses.

Publication of information by Erowid about human use of these chemicals is not intended to endorse their non-laboratory use.

Consider carefully before choosing to use these substances.

and from their Research Chemical FAQ

What are research chemicals?

When used to describe recreationally used psychoactive drugs, the term “research chemicals” generally refers to substances that haven’t yet been thoroughly studied. The term “research chemical” partially came from the fact that some substances on the recreational markets were drugs that had been discovered in labs and only examined in test-tube (in vitro) or low-level animal studies.

Some are very new, while others may have been around for years but haven’t had adequate enough medical investigation to quantify health risks, have not been consumed by many people over a long period, or had much data accumulated about their use. Little is known about them, and a good deal of what is known is based only on first-hand psychonautical reports. Scant to no research has been completed on the toxicology or human pharmacology of these drugs. Few, if any, formal human or animal studies have been done. Because of this, some have suggested that they would more appropriately be called “unresearched chemicals”. Another term for them is “experimental chemicals”, and this may better communicate the unknown risks associated with ingesting these drugs.

Unlike better-known drugs such as ecstasy (MDMA), which has been taken by millions of people over the last 30+ years, or marijuana which has been used by billions of people over millennia, in some cases the most novel of research chemicals may only have been used by several dozen people for a few months. The risks involved with research chemicals are greater than with many other drugs, since they’re unknowns. …

Are research chemicals safe to ingest?

No! While no drug use can categorically be characterized as “safe”, using research chemicals may be riskier than using older, better-studied drugs. This is not to say that the chemicals themselves are necessarily more dangerous… the risk lies in the fact that very little is known about them. There haven’t been enough people using them in high enough doses for long enough periods of time for us to have an idea what sort of damage the chemicals are capable of producing. When one takes a new and unstudied drug, one makes oneself a human guinea pig. The drug may be perfectly safe. It may even be beneficial. On the other hand, after three uses one might suddenly find one’s body frozen-up with symptoms resembling Parkinson’s disease. If you think this is an exaggeration, do some research on MPTP, a neurotoxic by-product that was produced during underground synthesis of the opioid MPPP, which contributed to the 1984 change in law that allowed the DEA to have “emergency scheduling” powers.

When taking a research chemical, one is stepping into the unknown, and could be the unfortunate person to discover a new drug’s lethal dose. One could find oneself addicted. Or, if one overdoses and ends up at the hospital, the doctors may only be able to guess at the appropriate course of treatment. Some drugs, like Cannabis, LSD, and psilocybin, have a wide safety range over which there is little to no possibility of pharmacologically induced death (perhaps 1,000 times or more the active dose), while other substances become dangerous at much lower amounts such as mescaline (perhaps 24 times the active dose), MDMA (perhaps 16 times the active dose) alcohol (perhaps 10 times the active dose), GHB (perhaps 8 times the active dose) or iv heroin (perhaps 6 times the active dose). Accidental overdoses happen to most people who consume psychoactives for long enough, and overdoses of research chemicals have unknown consequences. One who is not prepared to accept these risks should avoid taking research chemicals.

Believe it or not, a variety of research chemicals, with little to no history of human use, is what the New Zealand government has just approved for sale to the general public. (See here.) I listed some of them in my previous post. Here they are again.

PB-22
AB-FUBINACA
5F-PB-22
CP-55,244
an analogue of ADB-FUBINACA
AB-005
4F-AM-2201
CL-2201
LDD-3
SGT-7
SGT-19
SGT-24
SGT-42
SGT-55
SGT-56

What do we know about PB-22 (also known as QUPIC)?

No information regarding the in vitro or in vivo activity of QUPIC has been published, and only anecdotal reports are known of its pharmacology in humans or other animals.

The physiological and toxicological properties of this compound are not known.

What do we know about AB-FUBINACA?

It was originally developed by Pfizer in 2009 as an analgesic medication, but was never pursued for human use.

(BTW, it looks like Pfizer has a 2009 international patent on AB-FUBINACA and related indazole derivatives with cannabinoid (CB)1 receptor binding activity. Pfizer and the Psychoactive Substances Regulatory Authority—working together for a healthier world.)

What do we know about 5F-PB-22?

No information regarding the in vitro or in vivo activity of 5F-PB-22 has been published, and only anecdotal reports are known of its pharmacology in humans or other animals.

What do we know about CP-55,244?

It has analgesic effects and is used in scientific research.

What do we know about ADB-FUBINACA (or its analogue (S)-N-(1-amino-3, 3dimethyl-1-oxobutan-2-yl)-1-(5-fluoropentyl-1H-indole-3-carboxamide)?

Nothing is known of the pharmacological activity of ADB-FUBINACA in humans or other animals.

What do we know about AB-005?

No information regarding the in vivo activity of AB-005 has been published, and only anecdotal reports are known of its psychoactivity in humans.

What do we know about 4F-AM-2201? We know its chemical structure. It’s a fluoro analogue of AM-2201.

The toxicity of AM-2201 is still a matter of debate and there may be long term side effects.

What do we know about CL-2201, LDD-3, or any of the chemicals in the SGT series? Nothing whatsoever. In fact, the SGT series might as well be named the SFA series.

Now, please don’t get me wrong.

I’m a psychoactive substances enthusiast and I’ve tested a few research chemicals myself in the past. But I did so fully cognizant of the risks. I exercised due caution. (Mostly.) And I’m unscathed. (Pretty much.)

I’m a libertarian and I think that ALL drugs should be legal. And that what drugs are made widely available to the general public should be decided by a responsible, self-regulating legal highs industry. But what responsible, self-regulating legal highs industry would even dream of peddling untested research chemicals to the general public?

Sadly, what we have now is the polar opposite of my envisaged libertopia. Everything government touches turns to crap. Untested research chemicals are the only psychoactive substances the legal highs industry is allowed to offer for sale. All the safe recreational drugs have been banned. So the legal highs industry is caught between a rock and a hard place. Thanks to the prohibitionist tendencies of the New Zealand government, which is demonstrably unfit to have any involvement whatsoever in regulating the sale and use of psychoactive substances.

The Psychoactive Substances Act is a sick joke. On you.

What have you been smoking?

Everything government touches turns to crap

Welcome to Part 4 of the series. This one’s a little different. Different because this time you know what you’ve been smoking *before* you smoke it! And that’s how it should be.

The list below is sourced from the Interim Product Approvals page on the Ministry of Health website.

The status of (products that contain) the following 10 chemicals is ‘Licence issued’.

PB-22 1-pentyl-1H-indole-3-carboxylic acid 8-quinolinyl ester
AB-FUBINACA N-[(1S)-1-(aminocarbonyl)-2-methylpropyl]-1-[(4-fluorophenyl)methyl]-1H-indazole-3-carboxamide
5F-PB-22 1-(5-fluoropentyl)-1H-indole-3-carboxylic acid 8-quinolinyl ester
CP-55,244 (2S,4S,4aS,6R,8aR)-6-(hydroxymethyl)-4-[2-hydroxy-4-(2-methyloctan-2-yl)phenyl]-1,2,3,4,4a,5,6,7,8,8a-decahydronaphthalen-2-ol
* (S)-N-(1-amino-3, 3dimethyl-1-oxobutan-2-yl)-1-(5-fluoropentyl-1H-indole-3-caboxamide
AB-005 [1-[(1-methyl-2-piperidinyl)methyl]-1H-indol-3-yl](2,2,3,3-tetramethylcyclopropyl)-methanone
SGT-24
SGT-42
CL-2201
Fluoropentyl, fluoro-1-naphthoyl

The status of (products that contain) the following 6 chemicals is ‘Under consideration’.

LDD/3
1-(5-fluoropenty)-3-(4-fluoro-1-naphthoyl)indole
SGT-7
SGT-19
SGT-55
SGT-56

There’s no doubt that the Psychoactive Substances Act is a watershed. Whereas previous posts were lists of synthetic cannabinoids that the government had *banned*, this is a list of synthetic cannabinoids that the government has *approved*. It’s unprecendented! But is it a good?

You might think that as both a libertarian and a psychoactive substances aficionado I’d be all for this ground-breaking, world-leading legislation. But I’m not. I haven’t resiled from my previous assertion that, when all is said and done, the Psychoactive Substances Act is pure evil. Here’s why.

Succinctly (in the words of Ringo Starr), “everything government touches turns to crap.”

Let’s take a closer look at the list.

Chemically speaking, we know the structure (identity) of PB-22, AB-FUBINACA, 5F-PB-22, CP-55,244 and AB-005. But what about SGT-7, SGT-19, SGT-24, SGT-42, SGT-55, SGT-56 and LDD/3? No one but the manufacturer seems to know what they are. I doubt that even the Ministry of Health knows what they are. Mere names mean nothing. See that bird? There is a difference between the name of the thing and what goes on.

What about CL-2201? No idea. I’d hazard a guess that it’s a chlorine analogue of AM-2201. Who knows?

What about Fluoropentyl, fluoro-1-naphthoyl? Chemically speaking, this is pure gibberish.

Essentially, the government has approved for manufacture, sale and use a bunch of *unidentified* chemicals. But it gets worse.

PB-22 BB-22

The compound on the left is PB-22 which has interim approval. The compound on the right is BB-22 which was banned as from 9 May 2013 by Peter Dunne. They are structurally similar. They are analogues.

Supposedly, under the now repealed section 4C of the Misuse of Drugs Act 1975, Peter Dunne was (with respect to BB-22) “satisfied that the substance, preparation, mixture, or article that is to be specified in the notice poses, or may pose, a risk of harm to individuals, or to society.” According to the Ministry of Health FAQ, PB-22 is “shown to pose no more than a low risk of harm to people using [it]” but BB-22 is “known to have adverse effects on people using [it].” How’s that supposed to work? I call bullshit.

But it gets even worse.

AB-005 XLR-11_structure

The compound on the left is AB-005 which has interim approval. The compound on the right is XLR-11 which was banned as from 13 July 2012 by Peter Dunne. They are structurally similar. They are analogues.

The problem here is that XLR-11 has been linked to acute kidney injury in some users. Now the Ministry of “Health” has seen fit to approve an analogue of a suspected kidney toxin for human use. But it’s legal so it must be safe, right? Yeah right.

The Psychoactive Substances Act has nothing to do with your freedom or your health. It has everything to do with big government and mammon worship.

The government has lost the War on Drugs. Now it’s taking an “if you can’t beat ’em, join ’em” approach. And we should be afraid. Very afraid.